News

Selected press releases and news stories

This page is a work in progress and in the process of being updated. There are many news stories we have not posted here yet.

 

How many antibodies work after antibody conjugation?

August 1, 2007

A commentary about our Nano Letters paper by Pathak, Davidson, and Silva was featured in the American Chemical Society (ACS) journal Analytical Chemistry. The paper describes a molecular method for estimating the number of functionally bound antibodies chemically conjugated to quantum dot nanocrystals. Quantum dots are fluorescent nanoparticles that offer unique advantages for imaging cells and sub-cellular structures, but as our paper showed it is critical to make sure that the nanoparticles are correctly formulated. Otherwise non-specific effects can lead to misleading and reproducible false positive artifact labeling.

 

S Pathak, MC Davidson, and GA Silva (2007) Characterization of the functional binding properties of antibody conjugated quantum dots. Nano Letters 7:1839-1845. PDF

Gabriel Silva